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The positive effect of soybean protein hydrolysates-alcium complexes on bone mass of rapidly growing
来源:Food Funct.,2013,4,1245
发布时间:2015-10-22 15:22:04
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Ying Lv,#a  He Liu,#b  Jianhua Ren,#b  Xin Lib  and  Shuntang Guo*b

  

a.Beijing Key Laboratory of Agricultural Product Detection and Control of Spoilage Organisms and Pesticide Residue, College of Food Science and Engineering, Beijing University of Agriculture, 11 Beinong Road, Changping District, Beijing, 102206, China;

b.College of Food Science & Nutritional Engineering, China Agricultural University, 17 Qinghua East Road, Haidian District, Beijing, 100083, China.

E-mail:shuntang@cau.edu.cn; Fax: +86-10-62737634; Tel: +86-10-62737634
#. These authors contributed equally to this work.

Abstract

It was previously found that soybean protein hydrolysates (SPHs) can bind with calcium to form soluble complexes and promote calcium uptake by Caco-2 cells. However, the role of SPHs-alcium complexes on bone mass still needs to be explored. Fast growing male and female rats (n=72) were assigned to eight groups: Control, lactic acid calcium (LCa), SPHs-alcium complexes (SPHCa) and casein phosphopeptides calcium (CPPCa). After four weeks treatment, oral administration of SPHCa significantly increased femur BMD of rats compared with Control and LCa groups (P< 0.05), while there are no obvious difference on the BMD of femur and lumbar vertebrae between SPHCa and CPPCa groups. Also, SPHCa showed a tendency to improve the mechanical properties of vertebra lumber for female rats. These findings suggest that the SPHs-alcium complexes might have positive effects on bone accretion of fast growing animals. This study brings new insight for better understanding the role of soybean protein itself on bone mass.